11 July, 1997
Russ Johnson (Dallas)
MedLine Search confirms link between High Carbohydrate
Intake and IBD
In a recent IBDlist digest, someone mentioned the free MedLine
link at the National Institute
of Health's National Library of Medicine.
I followed the link to MedLine and did a search there on Carbohydrate
and Diet and IBD. I found the following:
Eur J Gastroenterol Hepatol 7 (1): 47-51 (Jan 1995)
Dietary habits as risk factors for inflammatory bowel disease.
by Tragnone A, Valpiani D, Miglio F, Elmi G, Bazzocchi G,
Pipitone E, Lanfranchi GA
Division of Internal Medicine, Bellaria Hospital, University
of Bologna, Italy.
OBJECTIVE: To examine the influence of dietary factors in
Italian patients with ulcerative colitis and Crohn's disease.
DESIGN: We studied dietary habits immediately prior to the
onset of disease in 104 patients enrolled in a prospective,
epidemiological study of the incidence of inflammatory bowel
disease in Italy.
METHODS: Each patient was interviewed using a recall questionnaire
to provide information on the daily intake of nutrients. The
differences in diet between patients and healthy subjects
matched for age, sex and city of residence were determined.
RESULTS: Our data confirm that patients with Crohn's disease
and ulcerative colitis have a high intake of total carbohydrate,
starch and refined sugar. This resulted in a significantly
higher relative risk (P < 0.001) in both ulcerative colitis
and Crohn's disease patients. Total protein intake was significantly
higher in ulcerative colitis, but not in Crohn's disease patients,
than in controls. Fibre consumption did not differ between
patients and controls.
CONCLUSIONS: Our results confirm that carbohydrate consumption
is significantly higher in IBD patients than in healthy controls.
Ulcerative colitis patients also consumed more total protein
than controls. The pathogenetic significance of these findings,
however, remains unclear. ...
PMID: 7866810, MUID: 95171184